Can I read Biaryl formation using the suzuki protocol: Considerations of base, halide, and protecting group. on EtoBox?
Biaryl formation using the suzuki protocol: Considerations of base, halide, and protecting group. by John W. Benbow; Bonnie L. Martinez is a Chemistry article available to read on EtoBox.
What is Biaryl formation using the suzuki protocol: Considerations of base, halide, and protecting group. about?
The generation of aryl anions prior to quenching with a trialkyl borate has been shown to be sensitive to the composition of the aryl substrate. Aryl iodides containing remote benzyl ether substituents undergo trany-metallation with xc-BuLi to cleanly give the desired aryl anions whereas the corresponding bromides afford appreciable quantities of dianionic intermediates. The aryl boronic acids derived from alkylation of these anions subsequently undergo a palladium mediated coupling with aryl halides to provide good yields of the desired biaryls.
Who reads Biaryl formation using the suzuki protocol: Considerations of base, halide, and protecting group.?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- John W. Benbow; Bonnie L. Martinez
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)
- Published
- 1996
- Language
- EN
- Field
- Chemistry (Physical Sciences)