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Can I read Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial on EtoBox?

Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial by Björn Stessel; Maurice Theunissen; Audrey A. Fiddelers; Elbert A. Joosten; Alfons G. Kessels; Hans-Fritz Gramke; Marco A. Marcus is a Medicine article available to read on EtoBox.

What is Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial about?

## Background Strong opioids in the home setting after ambulatory surgery have rarely been studied for fear of hazardous adverse effects such as respiratory depression. ## Objectives We compared the efficacy of paracetamol/controlled-release (CR) oxycodone and paracetamol/naproxen for treatment of acute postoperative pain at home after ambulatory surgery. Secondary outcomes were adverse effects of study medication, treatment satisfaction, and postoperative analgesic compliance. ## Methods Patients undergoing ambulatory knee arthroscopy or inguinal hernia repair surgery (n = 105) were randomized into 3 groups: Group1 paracetamol/naproxen (n = 35), Group 2 paracetamol/CR oxycodone for 24 hours (n = 35), and Group 3 paracetamol/CR oxycodone for 48 hours (n = 35). Pain intensity at movement and at rest using a visual analog scale as well as satisfaction with postoperative analgesia and side effects were recorded for up to 48 hours postoperatively. Compliance with study medication was also assessed. ## Results For pain at movement and at rest, no significant differences were found between the paracetamol/naproxen group and either the paracetamol/CR oxycodone for 24 hours group (β = 2.6

Who reads Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial?

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Author
Björn Stessel; Maurice Theunissen; Audrey A. Fiddelers; Elbert A. Joosten; Alfons G. Kessels; Hans-Fritz Gramke; Marco A. Marcus
Publisher
Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0011-393X)
Published
2014
Language
EN
Field
Medicine (Health Sciences)

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