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Role of prognostic scores in predicting in-hospital mortality and failure of non-invasive ventilation in adults with COVID-19 by Francesca Innocenti; Cristian Lazzari; Elisa Paolucci; Anna De Paris; Alessia Lagomarsini; Federica Guerra; Patrizia Alleonato; Lisa Casalini; Michele Buggea; Francesca Caldi; Maurizio Zanobetti; Filippo Pieralli; Giulia Guazzini; Lisa Lastraioli; Fabio Luise; Alessandro Milia; Lucia Sammicheli; Lucia Maddaluni; Federico Lavorini; Riccardo Pini is a Medicine article available to read on EtoBox.

What is Role of prognostic scores in predicting in-hospital mortality and failure of non-invasive ventilation in adults with COVID-19 about?

We tested the prognostic performance of different scores for the identification of subjects with acute respiratory failure by COVID-19, at risk of in-hospital mortality and NIV failure. We conducted a retrospective study, in the Medical High-Dependency Unit of the University-Hospital Careggi. We included all subjects with COVID-19 and ARF requiring non-invasive ventilation (NIV) between March 2020 and January 2021. Clinical parameters, the HACOR score (Heart rate, Acidosis, Consciousness, Oxygenation, Respiratory Rate) and ROX index ((SpO2/FiO2)/respiratory rate) were collected 3 (-3) and 1 day (-1) before the NIV initiation, the first day of treatment (Day0) and after 1 (+1), 2 (+2), 5 (+5), 8 (+8) and 11 (+11) of treatment. The primary outcomes were in-hospital mortality and NIV failure. We included 135 subjects, mean age 69±13 years, 69% male. Patients, who needed mechanical ventilation, showed a higher HACOR score (Day0: 6 [5-7] vs 6 [6-7], p=.057; Day+2: 6 [6-6] vs 6 [4-6], p=.013) and a lower ROX index (Day0: 4.2±2.3 vs 5.1±2.3, p=.055; Day+2: 4.4±1.2.vs 5.5±1.3, p=.001) than those with successful NIV. An HACOR score >5 was more frequent among nonsurvivors (Day0: 82% vs 58%;

Who reads Role of prognostic scores in predicting in-hospital mortality and failure of non-invasive ventilation in adults with COVID-19?

Author

Francesca Innocenti; Cristian Lazzari; Elisa Paolucci; Anna De Paris; Alessia Lagomarsini; Federica Guerra; Patrizia Alleonato; Lisa Casalini; Michele Buggea; Francesca Caldi; Maurizio Zanobetti; Filippo Pieralli; Giulia Guazzini; Lisa Lastraioli; Fabio Luise; Alessandro Milia; Lucia Sammicheli; Lucia Maddaluni; Federico Lavorini; Riccardo Pini

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)