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Distribution Patterns of Vimentin‐immunoreactive Structures in the Human Prosencephalon During the Second Half of Gestation by NORBERT ULFIG; FRANK NEUDÖRFER; JÜRGEN BOHL is a scholarly article available to read on EtoBox.

What is Distribution Patterns of Vimentin‐immunoreactive Structures in the Human Prosencephalon During the Second Half of Gestation about?

Neuronal migration is guided by long radially oriented glial fibres. During late stages of development radial glial cells are transformed into astrocytes. A predominant intermediate filament protein within radial glial cells and immature astrocytes is vimentin. In this study fetal brain sections were used to demonstrate the transient features of vimentin‐positive radial glia. In the lower half of the cerebral wall of the 6th gestational month bundles, curvature, and crossing of vimentin‐positive fibres are regularly seen. Moreover, fibres terminating on vessels are observed. In the upper half fibres are radially oriented; when ascending towards the pial surface the number and diameter of fibres appears conspicuously decreased. Radially aligned fibres display numerous varicosities. In the 8th month the bulk of vimentin‐positive fibres is encountered next to the ganglionic eminence and below isocortical cerebral fissures. The dentate gyrus is conspicuous due to its high amount of immunolabelled fibres. Furthermore, densely packed fibres are visible within the internal and external capsule and in the vicinity of the anterior commissure. Radial glial somata are found in the proliferati

Author

NORBERT ULFIG; FRANK NEUDÖRFER; JÜRGEN BOHL

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0021-8782)

Published

1999

Language

EN