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Embryonic expression patterns of the drosophila decapentaplegic gene: Separate regulatory elements control blastoderm expression and lateral ectodermal expression by P. David Jackson; Dr. F. Michael Hoffmann is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract Patterns of __decapentaplegic (dpp)__ transcripts derived from the intact gene were compared to the patterns of transcripts generated by partial __dpp__ transgenes in Drosophila embryos. Sequences closest to the __dpp__ coding regions, the __dpp__ hin region, were sufficient to express __lacZ__‐tagged mRNA in patterns indistinguishable from the patterns of endogenous __dpp__ expression in the dorsal and terminal cells at the blastoderm stage, in the dorsal ectoderm during germ band elongation, and in narrow stripes of ectodermal cells along the dorsal edge of the ectoderm and at the boundary between the lateral and ventral neurogenic regions during germ band shortening. The latter pattern of expression responded to the segment polarity genes __naked__ and __wingless__. However, these __dpp__ sequences were not sufficient to drive __lacZ__‐tagged mRNA expression in other cells normally expressing __dpp__, including cells in the gnathal segments, the clypeolabrum, the foregut, the midgut visceral mesoderm, and the hindgut. Two separate regulatory regions were found in the __dpp__ hin region. A 479 bp region upstream of the promoter was necessary for the segmented pattern

Who reads Embryonic expression patterns of the drosophila decapentaplegic gene: Separate regulatory elements control blastoderm expression and lateral ectodermal expression?

Author

P. David Jackson; Dr. F. Michael Hoffmann

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1058-8388)

Published

1994

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)