About this document
Non-Selective Drug Effects on NE Release by saheedsheriffajibola is a document available to read on EtoBox.
The document explains the effects of a non-selective drug that blocks both α₁ and α₂ receptors. The blockade of α₂ leads to increased norepinephrine (NE) release, while α₁ blockade prevents NE from causing vasoconstriction, resulting in massive vasodilation and decreased blood pressure. This causes orthostatic hypotension and increased heart rate due to NE acting on β₁ receptors instead of α₁.
- Author
- saheedsheriffajibola
- Language
- EN