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Creatine kinase isozymes in pipid frogs: Their genetic bases, gene expressional differences, and evolutionary implications by J. Wolff; Dr. H. R. Kobel is a Environmental Science article available to read on EtoBox.

What is Creatine kinase isozymes in pipid frogs: Their genetic bases, gene expressional differences, and evolutionary implications about?

Pipid frogs possess a creatine kinase isozyme repertory with a complexity paralleled only by teleostean fish. The effects of allelic polymorphism on their isozymes as well their differential solubility and resistance to heat denaturation suggest that species of Xenopus have at least four different CK loci. Each locus has its own tissue pattern of expression. CK-I isozymes are found only in the eye and stomach of Xenopus, in the stomach but not the eyes of Pipa and Hymenochirus, and the latter appears to have this isozyme in the liver also. The tissue expression of CK-I1 and CK-IV, respectively, resembles that of CK-A and CK-C of fish and that of CK-M (muscle) and CK-B (brain) of higher vertebrates. CK-I11 shows a striking developmental transition. In Xenopus heart muscle, additional CK isozymes are present that do not appear to be heterodimers. These may represent the contributions of additional creatine kinase genes or of epigenetic modification of other isozymes. The general tissue patterns of isozyme expression are similar but unique for each Xenopus species. The presumed allotetraploid species have essentially the same number of CK isozymes as the diploid X. tropicalis, suggest

Who reads Creatine kinase isozymes in pipid frogs: Their genetic bases, gene expressional differences, and evolutionary implications?

It is typically read by researchers, students, and practitioners in Environmental Science.

Author
J. Wolff; Dr. H. R. Kobel
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-104X)
Published
1985
Language
EN
Field
Environmental Science (Life Sciences)

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