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Clinical Manifestations in Neuropathologically Defined Subgroups of Vascular Dementia by Ulla Andin; Lars Gustafson; Arne Brun; Ulla Passant is a Medicine article available to read on EtoBox.

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## Aims: To study cardio-cerebrovascular disease and clinical features, such as falls, dizziness/unsteadiness, urinary incontinence, hallucinations/delusions and delirium in neuropathologically defined subgroups of vascular dementia (vad): pure small vessel dementia (svd), combined svd and alzheimer's disease (svd-ad), pure large vessel dementia (lvd) and pure hypoxic hypoperfusive dementia (hhd), and to analyse the clinical differences between these groups. ## Materials and methods: From 175 consecutive cases with neuropathologically verified vad cases with pure svd (n = 36) and svd-ad (n = 38) with varying severity of ad pathology were selected and studied with respect to cardio-cerebrovascular and other clinical features. furthermore, a comparison between pure svd, pure lvd (n = 7) and pure hhd (n = 6) was made. ## Results: Neither cardiovascular symptoms, hypertension, transitoric ischemic attacks (tia) nor complete cerebrovascular lesions (cvl) differed significantly between the pure svd and svd-ad groups. however, a wide variation of clinical features were reported. the prevalence of cardiovascular features varied markedly in the pure groups, with the highest prevalence consi

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Author

Ulla Andin; Lars Gustafson; Arne Brun; Ulla Passant

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0885-6230)

Published

2006

Language

EN

Field

Medicine (Health Sciences)