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KPNB1ATF4 Induces BNIP3dependent Mitophagy To Drive Odontoblastic Differentiation in Dental Pulp Stem Cells - 2024 - BioMed Central LTD by hernanhernandezmd is a document available to read on EtoBox.
This research article investigates the role of KPNB1-ATF4 in promoting BNIP3-dependent mitophagy, which is essential for the odontoblastic differentiation of dental pulp stem cells (DPSCs). The study demonstrates that ATF4 directly regulates BNIP3 expression, enhancing mitophagy and mitochondrial function, thereby facilitating DPSC differentiation. These findings provide insights into potential therapeutic strategies for dental pulp regeneration through the modulation of the KPNB1/ATF4/BNIP3 axis.
- Author
- hernanhernandezmd
- Language
- EN