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Not all adrenal incidentalomas require biochemical testing to exclude pheochromocytoma: Mayo clinic experience and a meta- analysis by Lucinda M. Gruber; Veljko Strajina; Irina Bancos; M. Hassan Murad; Benzon M. Dy; William F. Young; David R. Farley; Melanie L. Lyden; Geoffrey B. Thompson; Travis J. McKenzie is a Medicine article available to read on EtoBox.

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## Background: Excluding a pheochromocytoma is important when a patient presents with an incidentally discovered adrenal mass. however, biochemical testing for pheochromocytoma can be cumbersome, time consuming, or falsely positive. our objective was to determine if unenhanced computed tomography (ct) imaging alone can be used to rule out pheochromocytoma. ## Methods: We performed a retrospective study of all patients with a pathologically confirmed pheochromocytoma and unenhanced ct imaging who were treated at the mayo clinic between 1998 and 2016. additionally, we performed a systematic review and meta-analysis of original studies published after 2005 with patients who had adrenal masses, more than 10 patients with pheochromocytomas, and reported attenuation on unenhanced ct imaging in hounsfield units (hu). ## Results: In the mayo cohort, we identified 186 patients and 199 pheochromocytomas with unenhanced ct imaging. the mean unenhanced ct attenuation was 35±9 hu (range, 15-62), and only 15 tumors had attenuation ≤20 hu. the systematic review identified 26 studies (1,217 tumors), and 23 studies provided a mean unenhanced ct attenuation. the overall mean unenhanced ct attenuatio

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Author

Lucinda M. Gruber; Veljko Strajina; Irina Bancos; M. Hassan Murad; Benzon M. Dy; William F. Young; David R. Farley; Melanie L. Lyden; Geoffrey B. Thompson; Travis J. McKenzie

Publisher

AME Publishing Company

Published

2020

Language

EN

Field

Medicine (Health Sciences)