Can I read Circadian Profile of QT Interval and QT Interval Variability in 172 Healthy Volunteers on EtoBox?

Circadian Profile of QT Interval and QT Interval Variability in 172 Healthy Volunteers by HENDRIK BONNEMEIER; UWE K.H. WIEGAND; WIEBKE BRAASCH; AXEL BRANDES; GERT RICHARDT; JÜRGEN POTRATZ is a Medicine article available to read on EtoBox.

What is Circadian Profile of QT Interval and QT Interval Variability in 172 Healthy Volunteers about?

**BONNEMEIER, H., et al.: Circadian Profile of QT Interval and QT Interval Variability in 172 Healthy Volunteers.** __The limited prognostic value of QT dispersion has been demonstrated in recent studies. However, longitudinal data on physiological variations of QT interval and the influence of aging and sex are few. This analysis included 172 healthy subjects (89 women, 83 men; mean age__ __38.7 ± 15__ __years). Beat‐to‐beat QT interval duration (QT, QTapex [QTa], T~end~[Te]), variability (QTSD, QTaSD), and the mean R‐R interval were determined from 24‐hour ambulatory electrocardiograms after exclusion of artifacts and premature beats. All volunteers were fully active, awoke at approximately 7:00 am, and had 6–8 hours of sleep. QT and R‐R intervals revealed a characteristic day‐night‐pattern. Diurnal profiles of QT interval variability exhibited a significant increase in the morning hours (6–9 am; P < 0.01) and a consecutive decline to baseline levels. In female subjects the R‐R and T~end~ intervals were significantly lower at day‐ and nighttime. Aging was associated with an increase of QT interval mainly at daytime and a significant shift of the T wave apex towards the end of the

Who reads Circadian Profile of QT Interval and QT Interval Variability in 172 Healthy Volunteers?

Author

HENDRIK BONNEMEIER; UWE K.H. WIEGAND; WIEBKE BRAASCH; AXEL BRANDES; GERT RICHARDT; JÜRGEN POTRATZ

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0147-8389)

Published

2003

Language

EN

Field

Medicine (Health Sciences)