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Comparative Study of Endoscopic Surveillance in Hereditary Diffuse Gastric Cancer According To CDH1 Mutation Status 2016 by freddynande is a document available to read on EtoBox.

What is Comparative Study of Endoscopic Surveillance in Hereditary Diffuse Gastric Cancer According To CDH1 Mutation Status 2016 about?

This study investigates the effectiveness of endoscopic surveillance for hereditary diffuse gastric cancer (HDGC) based on CDH1 mutation status. It found that signet ring cell carcinoma (SRCC) was significantly more prevalent in CDH1 mutation carriers (61.1%) compared to non-carriers (9.7%), with a ten-fold increased risk of detection. The yield of SRCC decreased with successive endoscopies, suggesting that the frequency of surveillance could potentially be reduced for patients without a CDH1 mutation.

Author

freddynande

Language

EN