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The document discusses detecting active schistosome infection through detecting cell-free parasite DNA in serum and urine samples from areas highly endemic for Schistosomiasis japonicum in the Philippines. PCR was able to detect schistosome DNA in all Kato-Katz positive samples with 100% sensitivity. Schistosome DNA was also detected in some Kato-Katz negative samples, indicating cell-free DNA may be a promising diagnostic marker for active infection, especially light infections.
- Author
- James Chua
- Language
- EN