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Treatment Options for Diabetic Neuropathic Foot Ulcers: A Cost-Effectiveness Analysis by Jonathan Kantor; David J. Margolis is a Medicine article available to read on EtoBox.

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background. Diabetic foot ulcers are a common problem and result in more than 85,000 lower extremity amputations each year in the United States. Studies have suggested that between 25% and 50% of costs related to inpatient diabetes care may be directly attributable to the diabetic foot. Novel treatments for these wounds, while expensive, have been reported to improve healing rates, although no formal cost effectiveness analyses have been performed in order to address the cost effectiveness of a given therapy. objective. To estimate the cost effectiveness of common treatment strategies for diabetic neuropathic foot ulcers. methods. Four main options are available for the treatment of diabetic foot ulcers: (1) standard care (SC), (2) standard treatment in a specialized wound care center (WCC), (3) treatment with becaplermin, (4) or treatment with platelet releasate (PR). We utilized effectiveness data from published clinical trials, meta-analyses, and a database that includes data on 26,599 patients with these wounds. Effectiveness was assessed as a percentage of ulcers healed at 20 and 32 weeks. results. Baseline effectiveness (with 95% confidence intervals) for SC, becaplermin, PR,

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Author

Jonathan Kantor; David J. Margolis

Publisher

John Wiley and Sons; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Wolters Kluwer Health; Ovid Technologies (Wolters Kluwer Health); Elsevier BV (ISSN 1076-0512)

Published

2001

Language

EN

Field

Medicine (Health Sciences)