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This chapter discusses the principles of antimicrobial therapy in intensive care units, emphasizing the importance of initial empiric therapy followed by directed therapy based on pathogen identification. It highlights the role of antibiotic stewardship, optimal dosing, and the timing of administration to improve clinical outcomes while minimizing antibiotic resistance. The document also addresses the complexities of antibiotic selection and the impact of various pharmacologic properties on treatment effica

Author

tocap89

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EN