Opening book details…
Can I read Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial on EtoBox?
Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial by Yifang Hu; Wenwen Feng; Huanhuan Chen; He Shi; Lin Jiang; Xuqin Zheng; Xiaoyun Liu; Wensong Zhang; Yaoqi Ge; Yun Liu; Dai Cui is a Medicine article available to read on EtoBox.
What is Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial about?
## Abstract Selenium (Se) is an essential trace element in human. Recent studies of Se supplementation on the effect of Hashimoto’s thyroiditis (HT) have been reported, but the exact benefit is unclear as well as the underlying immunologic mechanism. We aimed to evaluate the clinical effect of Se supplement in patients with HT, and explore the potential mechanism against thyroid autoimmunity. A prospective, randomized‐controlled study was performed in patients with HT assigned to two groups. Se‐treated group (__n__ = 43) received selenious yeast tablet (SYT) for 6 months, whereas no treatment in control group (__n__ = 47). The primary outcome is the change of thyroid peroxidase antibody (TPOAb) or thyroglobulin antibody (TGAb). Second, thyroid function, urinary iodine, Se, Glutathione peroxidase3 (GPx3), and Selenoprotein P1 (SePP1) levels were measured during the SYT treatment. Meanwhile, regulatory T cells (Tregs) and their subsets activated Tregs (aTregs), resting Tregs, and secreting Tregs, as well as Helios and PD‐1 expression on these cells were also detected. The results showed that SYT treatment significantly decreased TPOAb, TGAb, and thyroid stimulating hormone (TSH) leve
Who reads Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto’s thyroiditis: A prospective randomized‐controlled trial?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Yifang Hu; Wenwen Feng; Huanhuan Chen; He Shi; Lin Jiang; Xuqin Zheng; Xiaoyun Liu; Wensong Zhang; Yaoqi Ge; Yun Liu; Dai Cui
- Publisher
- Wiley
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)