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Can I read Determination of Trimethoprim in Biological Fluids by High-performance Liquid Chromatography on EtoBox?
Determination of Trimethoprim in Biological Fluids by High-performance Liquid Chromatography by Robert E. Weinfeld; Teresita C. Macasieb is a Chemistry article available to read on EtoBox.
What is Determination of Trimethoprim in Biological Fluids by High-performance Liquid Chromatography about?
A rapid, sensitive, and specific high-performance liquid chromatographic -assay was developed for the determination of trimethoprim in blood, plasma, and urine using normalphase (adsorption) chromatography on a microparticulate silica column and UV monitoring at 280 nm. Trimethoprim is selectively extracted from the biological sample matrix at alkaline pH with chloroform, providing nearly quantitative extraction (>95%) and a sensitivity limit of 0.01 to 0.02 pg/ml blood or plasma, without interference from sulfonamides. \*Bactrim TM (Roche Laboratories Division, Hoffmann-La Roche), and SeptraTM (Burroughs Welcome); trimethoprimsulfametholrazole (1:5).
Who reads Determination of Trimethoprim in Biological Fluids by High-performance Liquid Chromatography?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Robert E. Weinfeld; Teresita C. Macasieb
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0378-4347)
- Published
- 1979
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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