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Bioconjugates of Cyclodextrins of Manganese Salen-type Ligand with Superoxide Dismutase Activity by Antonino Puglisi; Giovanni Tabbı̀; Graziella Vecchio is a Chemistry article available to read on EtoBox.

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6A,6B-Dideoxy-6A,6B-di[(N-salicylidene)amino]-b-cyclodextrin was synthesized and characterized by NMR, UV and CD spectroscopy in order to prepare a N,N 0 -bis-(salicylidene)ethane-1,2-diamine (SalenH 2 ) type ligand. The manganese(III) complex was synthesized and characterized by UV and cyclic voltammetry and compared to EUK-8. The superoxide dismutase (SOD)-like and catalase-like activities were tested by indirect assay. The cyclodextrin complex shows a larger solubility than EUK-8 and good SOD-like activity. Catalase activity is also shown.

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Author

Antonino Puglisi; Giovanni Tabbı̀; Graziella Vecchio

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0162-0134)

Published

2004

Language

EN

Field

Chemistry (Physical Sciences)