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This study investigates hypo-arousal during reward anticipation in patients with major depressive disorder (MDD) using pupillometry, finding a replicable negative correlation between pupil dilation and depressive symptom load. The results indicate that reduced pupil dilation is specifically associated with anhedonia symptoms, suggesting pupillometry could serve as a useful biomarker for assessing arousal deficits in MDD. Additionally, the research highlights the involvement of the salience network in the ph

Author

Laura Nicotera

Language

EN