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This study investigates the mechanisms of polyacrylamide (PAM) degradation using multi-omics analysis to identify the biodegradation pathway in Klebsiella sp. PCX, a bacterium capable of efficiently degrading PAM. Two unclassified amidohydrolases were characterized, showing significantly higher hydrolysis efficiency for PAM compared to small amides, with their structures and active sites elucidated. The findings provide a theoretical basis for PAM bioremediation and highlight the potential application of th

Author

Anne Nakagiri

Language

EN