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This review discusses the canonical and non-canonical functions of the non-coding RNA component TERC of the telomerase complex, highlighting its roles beyond telomere maintenance in cellular aging, immune regulation, and cancer. It also addresses the recent FDA approval of the first telomerase inhibitor, Imetelstat, and the therapeutic potential of targeting TERC in various diseases. The findings emphasize the need for further research into TERC

Author

debanjan mitra

Language

EN