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This document reviews the biotechnology applications of amino acids in protein purification and formulations. Specifically: 1. Certain amino acids act as "compatible solutes" that increase intracellular osmotic pressure without interfering with protein function, and also enhance protein stability. 2. Amino acids like sucrose, glycerol have traditionally been used to stabilize proteins during isolation and storage. 3. Arginine in particular was found to suppress protein aggregation during refolding and

Author

Sofia andrea Meza

Language

EN