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Adaptive Constrained Constructive Optimisation for Complex Vascularisation Processes by Talou, Gonzalo Daniel Maso (author);Safaei, Soroush (author);Hunter, Peter John (author);Blanco, Pablo Javier (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Adaptive Constrained Constructive Optimisation for Complex Vascularisation Processes about?

Mimicking angiogenetic processes in vascular territories acquires importance in the analysis of the multi-scale circulatory cascade and the coupling between blood flow and cell function. The present work extends, in several aspects, the Constrained Constructive Optimisation (CCO) algorithm to tackle complex automatic vascularisation tasks. The main extensions are based on the integration of adaptive optimisation criteria and multi-staged space-filling strategies which enhance the modelling capabilities of CCO for specific vascular architectures. Moreover, this vascular outgrowth can be performed either from scratch or from an existing network of vessels. Hence, the vascular territory is defined as a partition of vascular, avascular and carriage domains (the last one contains vessels but not terminals) allowing one to model complex vascular domains. In turn, the multi-staged space-filling approach allows one to delineate a sequence of biologically-inspired stages during the vascularisation process by exploiting different constraints, optimisation strategies and domain partitions stage by stage, improving the consistency with the architectural hierarchy observed in anatomical structu

Who reads Adaptive Constrained Constructive Optimisation for Complex Vascularisation Processes?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Talou, Gonzalo Daniel Maso (author);Safaei, Soroush (author);Hunter, Peter John (author);Blanco, Pablo Javier (author)
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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