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This study investigates the harmful effects of proton pump inhibitors (PPIs), specifically esomeprazole and lansoprazole, on male fertility in Wistar rats. Results indicate that subchronic exposure to these medications leads to significant declines in sperm count, motility, and testosterone levels, alongside increased oxidative stress markers and hormonal imbalances. The findings suggest that PPIs may cause reproductive toxicity in males, warranting further investigation into their long-term effects on fert

Author
regulatory
Language
EN

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