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Thy-1 Regulates Fibroblast Apoptosis in Lung by dupuytren is a document available to read on EtoBox.

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This document discusses how the cell surface protein Thy-1 interacts with the death receptor Fas in lipid rafts to regulate fibroblast apoptosis and the resolution of lung injury. Experiments showed that Thy-1 expression promotes apoptosis in lung fibroblasts through Fas, Bcl, and caspase pathways. Mice lacking Thy-1 had decreased myofibroblast apoptosis and failed resolution of bleomycin-induced lung fibrosis.

Author
dupuytren
Language
EN