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Can I read Ovarian Sex Steroids and Atherosclerosis on EtoBox?
Ovarian Sex Steroids and Atherosclerosis by M. Riedel; W. Rafflenbeul; P. Lichtlen is a Medicine article available to read on EtoBox.
What is Ovarian Sex Steroids and Atherosclerosis about?
Estrogens have been found to protect against atherosclerosis in a variety of animal models, and these antiatherogenic properties have been confirmed by epidemiological and clinical studies in women as well. Since the estrogen-induced changes of plasma lipid and lipoprotein levels do not fully account for the prevention of atherosclerosis, additional effects must be assumed. Experimental studies suggest various direct vascular actions. Estrogens enhance the endothelial degradation of low-density lipoprotein cholesterol, and preliminary data indicate antioxidative actions on low-density lipoprotein particles in macrophages. They suppress intimal proliferation and extracellular matrix production in the arterial wall and induce marked vasodilatation in systemic and coronary arteries. Adverse effects on hemostatic factors described with high doses and synthetic compounds are not evident during hormonal replacement in postmenopausal women, in whom an es-tradioMnduced inhibition of platelet aggregation may even have beneficial clinical effects. The role of progesterone and other progestogens in the progession of atherosclerosis is controversial. Despite a partial antagonism to estrogen-in
Who reads Ovarian Sex Steroids and Atherosclerosis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- M. Riedel; W. Rafflenbeul; P. Lichtlen
- Publisher
- Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 1432-1440)
- Published
- 1993
- Language
- EN
- Field
- Medicine (Health Sciences)