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What is HMG CoA Reductase Inhibition Mediated Hypocholesterolemic Potential of Myricetin and Quercetin in Silico and in Vivo Studies about?

The study investigates the hypocholesterolemic potential of myricetin and quercetin through HMG-CoA reductase inhibition using both in-silico and in-vivo methods. Results indicate that myricetin exhibits significant binding affinity and interaction capabilities with HMGCR, outperforming quercetin and atorvastatin in improving lipid profiles and reducing oxidative stress in hypercholesterolemic rabbits. The findings suggest that myricetin is a promising flavanol for managing cholesterol levels and oxidative

Author

ignasius.agyo.palmado

Language

EN