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Obesity and Inflammation: Change in Adiponectin, C-Reactive Protein, Tumour Necrosis Factor-Alpha and Interleukin-6 After Bariatric Surgery by Fátima Illán-Gómez; Manuel Gonzálvez-Ortega; Isabel Orea-Soler; Ma. Soledad Alcaraz-Tafalla; Aurora Aragón-Alonso; Mercedes Pascual-Díaz; Matías Pérez-Paredes; Ma. Luisa Lozano-Almela is a Medicine article available to read on EtoBox.

What is Obesity and Inflammation: Change in Adiponectin, C-Reactive Protein, Tumour Necrosis Factor-Alpha and Interleukin-6 After Bariatric Surgery about?

Background Obesity is associated with a low-grade inflammatory state. A causal association between inflammation and atherosclerosis has been suggested. The aim of this study was to evaluate changes in the proinflammatory profile of morbidly obese patients after weight loss following bariatric surgery. Methods In this study, we measured levels of adiponectin, high-sensitivity C-reactive protein (hs-CRP), tumour necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) and their relation to insulin resistance and lipid parameters in 60 morbidly obese women at baseline and 3, 6 and 12 months after gastric bypass. Results Twelve months after surgery, there was a significant increase in plasma levels of adiponectin (p<0.001) and highdensity lipoprotein cholesterol (p<0.01) and a significant decrease in levels of IL-6 (p<0.001), hs-CRP (p<0.001), cholesterol (p<0.001), triglycerides (p<0.001), low-density lipoprotein cholesterol (p<0.001), glucose (p<0.001), insulin (p<0.001) and homeostasis model assessment (HOMA; p<0.001). At 12 months, correlations were seen between IL-6 levels and the following: body mass index (BMI) (r00.53, p<0.001), insulin (r00.51, p<0.001) and HOMA (r00.55, p<0.001

Who reads Obesity and Inflammation: Change in Adiponectin, C-Reactive Protein, Tumour Necrosis Factor-Alpha and Interleukin-6 After Bariatric Surgery?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Fátima Illán-Gómez; Manuel Gonzálvez-Ortega; Isabel Orea-Soler; Ma. Soledad Alcaraz-Tafalla; Aurora Aragón-Alonso; Mercedes Pascual-Díaz; Matías Pérez-Paredes; Ma. Luisa Lozano-Almela
Publisher
Springer Science and Business Media LLC
Published
2012
Language
EN
Field
Medicine (Health Sciences)

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