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Ultrastructure of the Neuroglial Fatty Metamorphosis (Virchow) in the Perinatal Period by H. Schneider; J. Sperner; J. U. Drszus; H. Schachinger is a Medicine article available to read on EtoBox.

What is Ultrastructure of the Neuroglial Fatty Metamorphosis (Virchow) in the Perinatal Period about?

The ultrastructure of neuroglial fatty metamorphosis (GFM) has been investigated in the telencephalic white matter of 12 premature and mature infants (gestational age 2240 weeks; survival 0-96 days). GFM was found in all cases apart from a 22-week-old fetus, and involves predominantly astrocytic cells (68.8 %), then glioblasts (43.5%), but only 7.4% of oligodendrocytes. GFM, therefore, seems to be independent of the myelination process and indicates the vulnerability of the immature neuroglial population in the metabolic and circulatory disorders of the perinatal period. Since GFM is found in almost all children dying within the early postnatal period, this subtle alteration reflects a special form of minimal brain damage. The relationship between GFM, astrocytic hypertrophy and periventricular leucomalacia and their role in the telencephalic leucoencephalopathy are discussed.

Who reads Ultrastructure of the Neuroglial Fatty Metamorphosis (Virchow) in the Perinatal Period?

Author

H. Schneider; J. Sperner; J. U. Drszus; H. Schachinger

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1432-2307)

Published

1976

Language

EN

Field

Medicine (Health Sciences)