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This study investigates the mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori, focusing on the association of specific vacA types with cytotoxin production and peptic ulceration. The research identifies three families of vacA signal sequences and two families of middle-region alleles, revealing that certain genotypes correlate with higher cytotoxin activity and increased incidence of peptic ulcers. The findings suggest that the vacA genotype of H. pylori strains is significantly linked to th

Author

meuspans79

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EN