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The GetGoal Duo-2 trial evaluated the efficacy and safety of lixisenatide versus insulin glulisine as add-on therapies to basal insulin in patients with type 2 diabetes inadequately controlled on insulin glargine. Results showed that lixisenatide provided significant reductions in HbA1c with fewer hypoglycemic events and less weight gain compared to glulisine. This suggests that short-acting GLP-1 receptor agonists may be a preferred option for intensifying insulin therapy in this patient population.
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- qf6rtpjk68
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- EN