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Can I read Blue Light Differentially Alters Cellular Redox Properties on EtoBox?
Blue Light Differentially Alters Cellular Redox Properties by Jill B. Lewis; John C. Wataha; Regina L. W. Messer; Gretchen B. Caughman; Tetsuya Yamamoto; Stephen D. Hsu is a Medicine article available to read on EtoBox.
What is Blue Light Differentially Alters Cellular Redox Properties about?
## Abstract Blue light (λ = 380–500 nm) historically has been used to initiate polymerization of biomaterials and recently has been proposed as a therapeutic agent. New evidence suggests that cell‐type–specific responses result from redox changes induced by exposure to blue light. Cultured cells were exposed to defined doses of blue light, equivalent to exposure times of 10 s and 2 min, to achieve energies of 5 J/cm^2^ and 60 J/cm^2^, respectively, after which (a) viable cell number, (b) cellular protein profiles, (c) mitochondrial succinate dehydrogenase (SDH) activity, (d) total reactive oxygen species (ROS), and (e) induction of apoptosis were compared to that of nonexposed control cultures. Results showed that blue‐light exposure arrested monocyte cell growth and increased levels of peroxiredoxins. SDH activity of normal epidermal keratinocytes (NHEK) was slightly enhanced by blue light, whereas identical treatment of OSC2 oral tumor cells resulted in significant suppression of SDH activity. Blue‐light exposure generally induced higher levels of total ROS in OSC2 cells than in NHEK. Finally, only OSC2 cells exhibited signs of apoptosis via Annexin V staining following exposure
Who reads Blue Light Differentially Alters Cellular Redox Properties?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jill B. Lewis; John C. Wataha; Regina L. W. Messer; Gretchen B. Caughman; Tetsuya Yamamoto; Stephen D. Hsu
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1552-4973)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)