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What is Methamphetamine Addiction and CREB Pathways about?

This review summarizes research on the effects of methamphetamine (METH) self-administration on gene expression and neuroinflammation in the rat striatum. Studies found that extended access to METH self-administration in rats altered expression of genes involved in the cAMP response element binding protein (CREB) signaling pathway and neuroinflammatory responses in the brain. These changes may be involved in promoting METH addiction through neuroplasticity and cognitive impairments observed in human METH us

Author

Almas T

Language

EN