Opening book details…
Can I read CXC chemokine ligand 16: a Swiss army knife chemokine in cancer on EtoBox?
CXC chemokine ligand 16: a Swiss army knife chemokine in cancer by Arezoo Gowhari Shabgah; Maytham T. Qasim; Seyed Mojtaba Mostafavi; Angelina Olegovna Zekiy; Fatemeh Ezzatifar; Majid Ahmadi; Saeed Mohammadian Haftcheshmeh; Jamshid Gholizadeh Navashenaq is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is CXC chemokine ligand 16: a Swiss army knife chemokine in cancer about?
Today, cancer is one of the leading causes of death worldwide. Lately, cytokine and chemokine imbalances have gained attention amongst different involved pathways in cancer development and attracted much consideration in cancer research. CXCL16, as a member of the CXC subgroup of chemokines, has been attributed to be responsible for immune cell infiltration into the tumour microenvironment. The aberrant expression of CXCL16 has been observed in various cancers. This chemokine has been shown to play a conflicting role in tumour development through inducing pro-inflammatory conditions. The infiltration of various immune and non-immune cells such as lymphocytes, cancer-associated fibroblasts and myeloid-derived suppressor cells by CXCL16 into the tumour microenvironment has complicated the tumour fate. Given this diverse role of CXCL16 in cancer, a better understanding of its function might build-up our knowledge about tumour biology. Hence, this study aimed to review the impact of CXCL16 in cancer and explored its therapeutic application. Consideration of these findings might provide opportunities to achieve novel approaches in cancer treatment and its prognosis.
Who reads CXC chemokine ligand 16: a Swiss army knife chemokine in cancer?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Arezoo Gowhari Shabgah; Maytham T. Qasim; Seyed Mojtaba Mostafavi; Angelina Olegovna Zekiy; Fatemeh Ezzatifar; Majid Ahmadi; Saeed Mohammadian Haftcheshmeh; Jamshid Gholizadeh Navashenaq
- Publisher
- Cambridge University Press (CUP)
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)