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What is Understanding Sickle Cell Anemia Basics about?

Sickle cell disease (SCD) is a hereditary disorder characterized by the production of sickle hemoglobin (HbS) due to a mutation in the beta-globin gene, leading to distorted red blood cells (RBCs) under low oxygen conditions. It manifests as sickle cell anemia in homozygous individuals and sickle cell trait in heterozygous individuals, with symptoms appearing after six months of age. The disease causes chronic hemolytic anemia, increased susceptibility to infections, and chronic organ damage, with various c

Author

jgdmaitripatel482004

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EN