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What is Rat Liver Peroxisomes and Fatty Acid Oxidation about?

This document summarizes a study investigating whether rat liver peroxisomes catalyze the beta-oxidation of fatty acids. The authors purified peroxisomes from clofibrate-treated rat livers and tested for the presence of three enzymes involved in beta-oxidation (crotonase, beta-hydroxybutyryl-CoA dehydrogenase, and thiolase) using spectroscopic techniques. All three enzymes were detected in peroxisomes. Fractionation studies found the enzyme activities peaked in peroxisomes, ruling out mitochondrial contamin

Author
Black Widow
Language
EN