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Can I read Subcortical Contributions to Salience Network Functioning During Negative Emotional Processing on EtoBox?
Subcortical Contributions to Salience Network Functioning During Negative Emotional Processing by Sevil Ince; Trevor Steward; Ben J. Harrison; Alec J. Jamieson; Christopher G. Davey; James A. Agathos; Bradford A. Moffat; Rebecca K. Glarin; Kim L. Felmingham is a Neuroscience article available to read on EtoBox.
What is Subcortical Contributions to Salience Network Functioning During Negative Emotional Processing about?
Core regions of the salience network (SN), including the anterior insula (aINS) and dorsal anterior cingulate cortex (dACC), coordinate rapid adaptive changes in attentional and autonomic processes in response to negative emotional events. In doing so, the SN incorporates bottom-up signals from subcortical brain regions, such as the amygdala and periaqueductal gray (PAG). However, the precise influence of these subcortical regions is not well understood. Using ultra-high field 7-Tesla functional magnetic resonance imaging, this study investigated the bottom-up interactions of the amygdala and PAG with the SN during negative emotional salience processing. Thirty-seven healthy participants completed an emotional oddball paradigm designed to elicit a salient negative emotional response via the presentation of random, task-irrelevant negative emotional images. Negative emotional processing was associated with prominent activation in the SN, spanning the amygdala, PAG, aINS, and dACC. Consistent with previous research, analysis using dynamic causal modelling revealed an excitatory influence from the amygdala to the aINS, dACC, and PAG. In contrast, the PAG showed an inhibitory influence
Who reads Subcortical Contributions to Salience Network Functioning During Negative Emotional Processing?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Sevil Ince; Trevor Steward; Ben J. Harrison; Alec J. Jamieson; Christopher G. Davey; James A. Agathos; Bradford A. Moffat; Rebecca K. Glarin; Kim L. Felmingham
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Neuroscience (Life Sciences)