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Mouse Model of Anti-Obesity Effects of Blautia hansenii on Diet-Induced Obesity by Masaki Shibata; Naoki Ozato; Harutoshi Tsuda; Kenta Mori; Keita Kinoshita; Mitsuhiro Katashima; Yoshihisa Katsuragi; Shigeyuki Nakaji; Hayato Maeda is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Mouse Model of Anti-Obesity Effects of Blautia hansenii on Diet-Induced Obesity about?
Reportedly, a relationship exists between intestinal microflora and obesity-related lifestyle diseases. __Blautia__ spp. a major intestinal microbiota, accounts for 3–11% of human intestinal microflora. Epidemiological reports have described that people with more visceral fat have less __Blautia hansenii__ in their intestinal tract irrespective of age or gender. However, the effect of oral administration of heat-sterilized __Blautia hansenii__ on obesity has not been clarified. Therefore, the aim of this study was to evaluate the effects of dietary __Blautia hansenii__ administration on obesity in high-fat-diet-induced obesity in a mouse model. Heat-sterilized cells of __Blautia hansenii__ were used. C57BL/6J mice (normal mice, __n__ = 7) were fed with each experimental diet for nine weeks. Diets for experimentation were: normal-fat (NF) diets, high-fat (HF) diets, and high-fat + __Blautia hansenii__ (HF + __Blautia__) diets. The HF + __Blautia__ group was administered about 1 × 10^9^ (CFU/mouse/day) of __Blautia hansenii.__ During the periods of experimentation, body weight, food intake, water consumption, and fecal weight were recorded, and glucose tolerance tests were performed.
Who reads Mouse Model of Anti-Obesity Effects of Blautia hansenii on Diet-Induced Obesity?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Masaki Shibata; Naoki Ozato; Harutoshi Tsuda; Kenta Mori; Keita Kinoshita; Mitsuhiro Katashima; Yoshihisa Katsuragi; Shigeyuki Nakaji; Hayato Maeda
- Publisher
- MDPI AG
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)