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What is Biophysical Chemistry about?
The role of tryptophan in staphylococcal nuclease stability has not been fully elucidated. A single Trp residue at position 140 is critical to SNase structure, stability, and function. Mutants such as W140A,. F61W / W140A and Y93W /. W140A have unfolding, corrupted secondary and tertiary structures, diminished structural stability and. Attenuated catalytic activity
- Author
- Frontiers
- Language
- EN