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Biodegradable Hydrogel for Drug Delivery by joyhar9 is a document available to read on EtoBox.
This document summarizes a study that synthesized a biodegradable gum ghatti-cl-poly(AA-co-NIPAm)/GO hydrogel for combined delivery of metformin and sodium diclofenac. The hydrogel was characterized using various analytical techniques. Both drugs were released in a pH-dependent manner, with high release at pH 7.4. Drug release kinetics followed several models including zero-order and first-order. Both drugs showed Fickian diffusion mechanism at pH 7.4. Combining metformin and diclofenac may lower dosage nee
- Author
- joyhar9
- Language
- EN