Can I read Design and Characterization of a Microfluidic Biological System for Bone Tissue on EtoBox?

Design and Characterization of a Microfluidic Biological System for Bone Tissue by Odin Ramirez-Fernandez; Fabian Equihua-Guillen; Adrian Garcia-Lara; Esmeralda Zuñiga-Aguilar is a book available to read on EtoBox.

What is Design and Characterization of a Microfluidic Biological System for Bone Tissue about?

Tissue engineering has managed to revolutionize the transplantation and regenerative medicine, it is responsible for developing biomaterials to generate a promising approach for studying complex physiological processes in vitro. The design and application of biological systems evaluate a microfluidic platform based on organs physiology, modeling the nutrient distribution, and testing potential implants. The present investigation aims to design and characterize a biological system to simulate the microfluidic environment of the bone tissue. The system must provide the conditions for adequate cell regulation, to achieve this, adhesion, migration, proliferation, and differentiation are used, as well as the adequate delivery of bioactive factors such as growth and adhesion. A novel hydraulic circuit with radial flow and their components were designed in SolidWorks, then the pieces were calculated with the Navier-Stokes equations using ANSYS and COMSOL software, to have a laminar environment and their behavior using microfluidics and cells mimicking the bone structure. The components were generated by 3D printing and the additive stereolithography resin technique. According to the CFD s

Author

Odin Ramirez-Fernandez; Fabian Equihua-Guillen; Adrian Garcia-Lara; Esmeralda Zuñiga-Aguilar

Publisher

Springer International Publishing

Published

2023

Language

EN

ISBN

9783031469336

Subjects

Engineering, Medical, Medicine