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Sugar‐Assisted Ligation for the Synthesis of Glycopeptides by Ashraf Brik; Chi‐Huey Wong is a Chemistry article available to read on EtoBox.
What is Sugar‐Assisted Ligation for the Synthesis of Glycopeptides about?
## Abstract Chemical synthesis of glycoproteins from readily available materials is a powerful method for obtaining a pure product with full control of its atomic structure. Sugar‐assisted ligation (SAL) is an emerging approach that allows the synthesis of a large glycopeptide from two unprotected fragments. Contrary to other ligation methods that are limited to the use of a cysteine residue or depend on external auxiliary, SAL takes advantage of the existing sugars in glycopeptides to promote proximity between the two peptides to facilitate an amide bond formation.
Who reads Sugar‐Assisted Ligation for the Synthesis of Glycopeptides?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Ashraf Brik; Chi‐Huey Wong
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 0947-6539)
- Published
- 2007
- Language
- EN
- Field
- Chemistry (Physical Sciences)