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Minor and Trace Element Contents in Pituitary Gland of “Normal” Humans: an Evaluation of Analytical Data by M. Speziali; E. Sabbioni is a Chemistry article available to read on EtoBox.

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In the study of trace elements in the different human brain areas, a critical evaluation of the values available in the literature is of great importance in attempting to establish reliable baseline levels, i.e., Reference Values (RVs) for toxicological assessment studies. This paper reviews the published values of minor and trace elements in the pituitary gland (hypophysis) of bnormalQ humans. Eighteen published papers are taken into account, 15 of which refer to the entire gland, whereas in three of them, only the adenohypophysis is considered. It turns out that essential elements such as Cu, Fe, Se and Zn were more frequently determined, whereas As, Br, Ca, Co, Cr, Cs, K, Mg, Mn, Ni and Rb were seldom investigated. Mercury was determined by several authors because of the concern caused by Hg release from dental amalgam fillings. Most values were obtained by Neutron Activation Analysis (NAA), which appears to have played a pioneer role in this field. Literature data on trace element levels in pituitary gland are at present insufficient to establish RVs; rather, they can be considered only as indicative values. Future investigations based on large populations of control subjects,

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Author

M. Speziali; E. Sabbioni

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0026-265X)

Published

2005

Language

EN

Field

Chemistry (Physical Sciences)