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Ischemic acute tubular necrosis is a common cause of acute renal failure that can result from hypotension, hypovolemia, trauma, infections, and other conditions. On microscopy, the proximal tubules are dilated and flattened with reduced brush borders, resembling distal tubules. Granular casts and oxalate crystals may be present. Cellular necrosis is subtle, often involving individual cells. Toxic acute tubular necrosis is usually limited to specific nephron segments and involves overt cellular necrosis, par

Author

cedric

Language

EN