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Assessing Interobserver Variability in the Delineation of Structures in Radiation Oncology: A Systematic Review by Leslie Guzene; Arnaud Beddok; Christophe Nioche; Romain Modzelewski; Cedric Loiseau; Julia Salleron; Juliette Thariat is a Medicine article available to read on EtoBox.
What is Assessing Interobserver Variability in the Delineation of Structures in Radiation Oncology: A Systematic Review about?
Purpose The delineation of target volumes and organs at risk is the main source of uncertainty in radiation therapy. Numerous interobserver variability (IOV) studies have been conducted, often with unclear methodology and nonstandardized reporting. We aimed to identify the parameters chosen in conducting delineation IOV studies and assess their performances and limits. Methods and Materials We conducted a systematic literature review to highlight major points of heterogeneity and missing data in IOV studies published between 2018 and 2021. For the main used metrics, we did in silico analyses to assess their limits in specific clinical situations. Results All disease sites were represented in the 66 studies examined. Organs at risk were studied independently of tumor site in 29% of reviewed IOV studies. In 65% of studies, statistical analyses were performed. No gold standard (GS; ie, reference) was defined in 36% of studies. A single expert was considered as the GS in 21% of studies, without testing intraobserver variability. All studies reported both absolute and relative indices, including the Dice similarity coefficient (DSC) in 68% and the Hausdorff distance (HD) in 42%. Limitat
Who reads Assessing Interobserver Variability in the Delineation of Structures in Radiation Oncology: A Systematic Review?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Leslie Guzene; Arnaud Beddok; Christophe Nioche; Romain Modzelewski; Cedric Loiseau; Julia Salleron; Juliette Thariat
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)