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Current Practice in Benzodiazepine Receptor Agonists Deprescribing on Acute Geriatric Wards: a Cohort Study by François-Xavier Sibille; Anne Spinewine; Lorène Zerah; Laurentine Maljean; Didier Schoevaerdts; Marie de Saint-Hubert is a Medicine article available to read on EtoBox.
What is Current Practice in Benzodiazepine Receptor Agonists Deprescribing on Acute Geriatric Wards: a Cohort Study about?
## Abstract ## Background Benzodiazepine receptor agonist (BZRA) use is highly prevalent in hospitalised older people although these drugs are associated with numerous and serious adverse events. Deprescribing can reduce risks associated with chronic BZRA use. The aim of this study was to measure the prevalence of, and factors associated with, BZRA deprescribing in acute geriatric units. ## Methods During a one-year period, this multicentre retrospective study included patients aged ≥70 years, hospitalised in acute geriatric units, and using ≥1 BZRA on admission. BZRA deprescribing at discharge was defined as: ≥25% decrease in lorazepam-equivalent admission dose; discontinuation of all BZRAs; or cessation of a rescue prescription at discharge. BZRA cessation was defined as discontinuation of all BZRAs at discharge. We identified social, medical, geriatric and medication factors associated with BZRA deprescribing using logistic regression. ## Results In total, 561 patients were included (mean age: 85.3±5.9 years, 70% of women). BZRA deprescribing occurred in 240 (42.8%), including 85 with BZRA cessation (15.2%). Deprescribing occurred more frequently in patients with a BZRA-related
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- Author
- François-Xavier Sibille; Anne Spinewine; Lorène Zerah; Laurentine Maljean; Didier Schoevaerdts; Marie de Saint-Hubert
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)