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Prognostic Value Of Integrated Assessment Of Cardiac Magnetic Resonancederived Global Coronary Flow Reserve And Cardiopulmonary Exercise Testingderived Peak O2 Pulse In Patients With Acute Myocardial Infarction by Kazuki Matsuda; Tomoyo Sugiyama; Yoshihisa Kanaji; Masahiro Hoshino; Masahiro Hada; Tatsuhiro Nagamine; Yoshihiro Hanyu; Hiroki Ueno; Kai Nogami; Kodai Sayama; Tatsuya Sakamoto; Taishi Yonetsu; Tetsuo Sasano; Tsunekazu Kakuta is a Medicine article available to read on EtoBox.

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Background: The implication and prognostic value of cardiac magnetic resonance imaging (CMR)-derived global coronary flow reserve (G-CFR) in addition to cardiopulmonary exercise testing (CPET) variables remains unclear in patients with acute myocardial infarction (AMI). Methods: We investigated 127 patients with AMI who underwent primary or urgent percutaneous coronary intervention. All patients underwent CPET and post-intervention CMR. G-CFR was calculated as coronary sinus flow (CSF) during maximal hyperemia divided by CSF at rest by CMR. Peak O2 pulse was defined as peak ̇VO2 divided by peak heart rate by CPET. Major cardiac and cerebrovascular events (MACCE) were defined as composite endpoint of all-cause death, nonfatal myocardial infarction, re-hospitalization due to congestive heart failure, and stroke. The incidence of MACCE was evaluated during the follow-up period (median 2.8 years). Results: In a total of 127 patients, MACCE occurred in 14 patients (11.0%). Patients with MACCE had lower left ventricular ejection fraction (LVEF) (50 [43-59] vs. 58 [51-63] %, P=0.014), lower ], P=0.008), and lower peak O2 pulse (8.73±2.18 vs. 10.36±2.32 ml/beat, P=0.014) than patients wit

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Author

Kazuki Matsuda; Tomoyo Sugiyama; Yoshihisa Kanaji; Masahiro Hoshino; Masahiro Hada; Tatsuhiro Nagamine; Yoshihiro Hanyu; Hiroki Ueno; Kai Nogami; Kodai Sayama; Tatsuya Sakamoto; Taishi Yonetsu; Tetsuo Sasano; Tsunekazu Kakuta

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)