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What is Sparfloxacin Injection Formulation Study about?
1) The study aimed to develop a stable parenteral formulation of sparfloxacin, a water-insoluble fluoroquinolone antibiotic, using co-solvents. 2) Various co-solvents were evaluated for their ability to solubilize sparfloxacin. PEG-400 was selected and used in formulations along with ethyl alcohol. 3) The formulations were subjected to accelerated stability testing to predict shelf-life and evaluate the impact of heat, light, oxygen and antioxidants on stability. Sterilization by membrane filtration and
- Author
- Anggun
- Language
- EN