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What is Optimized Nanoparticles for IBD Therapy about?

This study focuses on the development and optimization of mesalamine-loaded polyelectrolyte complex nanoparticles aimed at targeted delivery for inflammatory bowel disease treatment. Using a central composite design approach, the nanoparticles were synthesized with chitosan and sodium carboxymethyl cellulose, and coated with Eudragit S-100 to enhance stability and colon-targeting properties. The optimized formulation demonstrated a significant encapsulation efficiency and a controlled drug release profile,

Author

afsarsiddiqu92

Language

EN