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Can I read Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study on EtoBox?
Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study by Alvarez-Madrazo, Samantha; Kavanagh, Kimberley; Siebert, Stefan; Semple, Yvonne; Godman, Brian; Maciel Almeida, Alessandra; Acurcio, Francisco de Assis; Bennie, Marion is a Medicine article available to read on EtoBox.
What is Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study about?
## Objectives: To understand patterns of subcutaneous (sc) biologics use over time in adults with inflammatory rheumatic musculoskeletal diseases receiving a homecare delivery service. ## Design: Retrospective cohort. ## Setting: Patients in secondary care receiving sc biologics in the largest scottish health board. ## Participants: A new bespoke cohort was created from routine data gathered as part of a health board homecare service database. patients over 18 years who received a supply of sc biologic from january 2012 to may 2015 with a diagnosis for rheumatoid arthritis (ra), psoriatic arthritis (psa) or ankylosing spondylitis (as) were included. ## Outcomes measured: A standardised framework was applied by measuring discontinuation rates, persistence using kaplan-meier analysis and cox regression and adherence using medication refill adherence (mra) and compliance rate (cr). ## Results: 751 patients were identified (as: 105, psa: 227, ra: 419) of whom 89.3% had more than one biologic delivery (median days' follow-up: as: 494; psa: 544; ra: 529) and 83.2% did not switch biologic. for all conditions, approximately half were persistent on their index biologic (52% as, 54% psa, 48%
Who reads Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study?
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- Author
- Alvarez-Madrazo, Samantha; Kavanagh, Kimberley; Siebert, Stefan; Semple, Yvonne; Godman, Brian; Maciel Almeida, Alessandra; Acurcio, Francisco de Assis; Bennie, Marion
- Publisher
- BMJ; BMJ Publishing Group; London: BMJ Publishing (ISSN 2044-6055)
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)